Rispoval IBR-Marker Inactivated

Rispoval IBR-Marker Inactivated
An inactivated Infectious Bovine Rhinotracheitis Marker (gE negative) vaccine.

One dose (2 ml) contains: Bovine Herpes Virus type 1 (BoHV-1), strain Difivac (gE-negative) to induce a geometric mean seroneutralising titre of at least 1:160 in cattle. Also contains the adjuvants aluminum hydroxide 14-24 mg and Quil A 0.25 mg, and the preservative thimerosal 0.2 mg.

Uses

For the active immunisation of cattle against Infectious Bovine Rhinotracheitis (IBR) to reduce the clinical signs and virus shedding and, in female cattle, to prevent abortions associated with BoHV-1 infection. The vaccination of pregnant cattle will prevent abortion associated with BoHV-1 infection as demonstrated during the second trimester of gestation following challenge 28 days after vaccination.

Duration of immunity: 6 months.

For booster immunisation after primary vaccination with Rispoval IBR Marker Live to reduce the virus shedding and the clinical signs associated with BoHV-1 infection in cattle. When using the combined vaccination scheme, protection against abortions has not been investigated.

Duration of immunity : 6 month after complete primary vaccination with Rispoval IBR Marker Live followed by 12 month after annual booster with Rispoval IBR Marker Inactivated.

Dosage and administration

Dose

Cattle over 3 months of age: 2 ml.

Route

Subcutaneous injection.

Shake the vaccine well before use.

Vaccination Scheme

The vaccination scheme consists of basic immunisation and booster vaccinations.

Basic Immunisation

Two doses, each of 2 ml, 3-5 weeks apart.

Booster vaccinations

Booster vaccinations of cattle having been administered the primary vaccination scheme using Rispoval IBR Marker Inactivated:

One dose of 2 ml at 6 monthly intervals.

Booster vaccinations of cattle having been administered the primary vaccination scheme using Rispoval IBR Marker Live:

Cattle having been administered the primary vaccination scheme using Rispoval IBR-Marker Live (according to the product information for this product) may be given booster vaccinations with Rispoval IBR-Marker Inactivated. These animals should be given a single dose booster vaccination with Rispoval IBR-Marker Inactivated 6 months after their initial vaccination course with Rispoval IBR-Marker Live. Thereafter, single dose booster vaccinations with Rispoval IBR-Marker Inactivated should be administered every 12 months.

It is recommended that all cattle in the herd are vaccinated.

Use only sterile needles and syringes for administration.

Avoid the introduction of contamination during use.

Due to the presence of maternal antibodies, the development of immunity in calves under 3 months of age may be impaired. These animals should be re-vaccinated at 3 months.

Method of administration

Shake the vaccine well before use. The liquid suspension is injected aseptically via the subcutaneous route.

Vaccination schemes summary

From 2 weeks to 3 months of age

      
Rispoval IBRm Vaccine Used

Revaccination Intervals

Primary vaccination (number of doses)

Booster vaccination at 3 months of age (number of doses)

Interval to next booster vaccination (vaccine)

All subsequent booster vaccinations (vaccine)

Live (Once IN)

Live (Once IM)

6 Months (Live IM)

6 Months (Live IM)

Live (Once IN)

Live (Once IM)

6 Months (Inactivated SQ)

12 months (Inactivated SQ)

From 3 months of age

    
Rispoval IBRm Vaccine used

Revaccination Intervals

Primary vaccination (number of doses)

Interval to first booster vaccination (vaccine)

All subsequent booster vaccinations (vaccine)

Live (Once IM)

6 Months (Live IM)

6 Months (Live IM)

Live (Once IM)

6 Months (Inactivated SQ)

12 Months (Inactivated SQ)

Inactivated (Twice with 3 - 5 Week Interval SQ)

6 Months (Inactivated SQ)

6 Months (Inactivated SQ)

Contra-indications, warnings, etc

Do not use in unhealthy animals.

Transient subcutaneous swelling up to 5 cm in diameter, which subsides within 14 days, may occur at the injection site in very rare cases. In very rare cases allergic reactions may occur as with other vaccines, therefore vaccinates should be observed for approximately 30 minutes following immunisation. In those cases, anti-allergics should be administered.

Immunosuppressive substances e.g. corticosteroids or Bovine Viral Diarrhoea modified live vaccines, should be avoided for a period of 7 days prior to and after vaccination as this may impair the development of immunity.

In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.

Withdrawal periods

Zero days.

Pharmaceutical precautions

Store in a refrigerator (+2°C to +8°C). Protect from frost, heat and light. Shelf-life after first opening the immediate packaging: 8 hours.

No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be decided on a case by case basis.

Do not mix with any other veterinary medicinal product.

Any unused product or waste material should be disposed of in accordance with national requirements.

For animal treatment only.

Keep out of reach and sight of children.

Legal category

POM-V

Packaging Quantities

Cartons containing 20 ml (10 dose) or 100 ml (50 dose) vials. Not all pack sizes may be marketed.