Rispoval Intranasal RS+PI3

A powder containing modified live Bovine parainfluenza type 3 virus (PI3V) virus, thermosensitive strain RLB103, between 105.0 and 108.6 CCID50 and modified live Bovine Respiratory Syncytial virus (BRSV), strain 375, between 105.0 and 107.2 CCID50, supplied with sterile diluent (water for injection and sodium chloride, 18 mg per 2 ml) for reconstitution.
*CCID50 : Cell Culture Infective Dose 50%

For active immunisation of maternally derived antibody positive or negative calves from 9 days of age against BRSV and PI3V, to reduce the mean titre and duration of excretion of both viruses.
Onset of immunity: 5 days for BRSV and 10 days for PI3V after a single vaccination.
Duration of protective immunity: 12 weeks following a single dose. The duration of protective immunity against the PI3V fraction may be reduced in MDA positive calves vaccinated before 3 weeks of age.

Reconstitute the vaccine by aseptically adding all the liquid to the vial containing the powder components. Shake well.
Vaccination programme:
A single dose of 2ml of reconstituted vaccine should be given intranasally using the intranasal applicators provided to cattle from the age of 9 days. It is recommended to change applicators between animals to avoid transmitting infectious organisms.

Do not use during pregnancy/lactation. Vaccinate only healthy animals.
Published evidence shows that on rare occasions repeated exposure to BRSV may trigger hypersensitivity reactions.
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
Withdrawal period
Zero days.