Chronogest CR 20mg Controlled Release (pack of 25)

Chronogest CR 20 mg controlled release vaginal sponge for sheep (Pack of 25).

Presentation

White cylindrical polyester polyurethane foam equipped with string.

Each polyester polyurethane sponge contains 20mg flugestone acetate.

Uses

In ewes and ewe-lambs, in combination with PMSG (Pregnant Mare Serum Gonadotrophin).

-Induction and synchronization of oestrus and ovulation (non-cycling ewes during seasonal anoestrus and ewe-lambs).

-Synchronisation of oestrus and ovulation (cycling ewes and ewe-lambs).

Dosage and administration

The dose is one sponge per animal irrespective of body weight, breed, type (dairy or meat) and season.

The sponge is inserted intra-vaginally using an applicator.

Duration of sponge residence is 14 days. At the end of the administration period, the sponge is gently removed by pulling on its string.

To obtain an optimal synchronisation of ovulation, an injection of PMSG (range 300-700 IU) is recommended (i.m.) at the time of sponge removal.

In case fixed time artificial insemination is applied, it is recommended to perform it 55 h after sponge removal.

Contra-indications, warnings, etc

The product can be used during lactation.

The use is not recommended during gestation.

The sponges should not be used in conjunction with alcohols, cresols, phenols, sheep dips or similar disinfectants.

The repeated treatment with the product combined with PMSG may trigger the appearance of PMSG antibodies in some ewes. This in turn may affect the time of ovulation and result in reduced fertility when combined with fixed time artificial insemination at 55 h following sponge removal.

The repeated use of sponges within one year has not been studied.

The use of a vaginal applicator designed for ewes or ewe-lambs is recommended to correctly insert sponges and to avoid vaginal injuries.

Withdrawal periods

For meat: 2 days after withdrawal of sponges.

For milk: zero hours, including the treatment time.

Operator warnings

Direct contact with the skin should be avoided. Personal protective clothing (single use gloves) should be worn when handling the product. If accidental contact with the skin occurs, wash the affected zone with soap and water. Wash hands after treatment and before meals. Human exposure to this product can affect fertility.

Women who are pregnant, or suspected to be pregnant, must not use the product.

For animal treatment only. Keep out of reach and sight of children.

Pharmaceutical precautions

Store below 25°C and in a dry place.

Store the product in its original immediate packaging.

Once packaging is opened, any unused product should be discarded.

Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

Legal category

POM-V

Packaging Quantities

Metallic polyester/low density polyethylene bags containing 25 sponges.